g6pd deficiency glutathione Glucose 6 Phosphate Dehydrogenase (G6PD) G6PD Deficiency • Glucose-6-phosphate dehydrogenase

G6PD Deficiency Glucose 6 phosphate dehydrogenase deficiency X linked recessive disorder Leads to low NADPH, impairing glutathione regeneration RBCs are vulnerable to oxidative damage Pathophysiology: In G6PD deficiency: No Glucose 6 Phosphate Dehydrogenase deficiency G6PD deficiency, features, Offending & Safe drugs Figure 1. G6pd Deficiency Does Not Affect the Cytosolic Glutathione or Thioredoxin Antioxidant Defense in Mouse Cochlea Journal of Neuroscience Correcting glucose 6 phosphate dehydrogenase deficiency with a small molecule activator Nature Communications

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